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Clobetasol propionate is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat skin inflammation and itching associated with skin conditions that respond to corticosteroids in people aged 12 and older. Clobetasol propionate was formerly sold under the brand name Temovate.

Clobetasol propionate is a highly potent corticosteroid. Clobetasol propionate is believed to work by suppressing immune system activity.

How do I take it?
Clobetasol propionate is applied topically to affected areas twice daily. Given this drug’s potency, the prescribing information recommends not using clobetasol propionate for more than two consecutive weeks. Always follow your doctor’s instructions when using clobetasol propionate.

Clobetasol propionate comes in the form of a cream or an ointment.

Side effects
The FDA-approved label for clobetasol propionate lists common side effects including acne, burning, itching, stinging, thinning and wrinkling of skin, visible depressions in the skin, skin cracking, numbness in the fingers, spider veins, and inflammation of hair follicles.

Rare but serious side effects for corticosteroids, especially more potent drugs like clobetasol propionate, include high blood sugar and reversible hypothalamic-pituitary-adrenal axis suppression (a dysfunction of the adrenal system). If you experience sudden weight gain, fatigue, muscle weakness, depression, or severe rashes or skin sores, call your doctor immediately.

For more details about this treatment, visit:

Clobetasol Topical — MedlinePlus

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